Article
HLA and MICA associations with head and neck squamous cell carcinoma.
Oral oncology - 1 Mar 2007
Reinders Judith, Rozemuller Erik H, Otten Henny G, van der Veken Lars T J N, Slootweg Pieter J, Tilanus Marcel G J
Abstract excerpt
Head and neck squamous cell carcinoma (HNSCC) is a very aggressive tumour arising from the epithelial lining of the upper aerodigestive tract. The precise mechanisms involved in the pathogenesis of HNSCC have not been elucidated. Previous studies observed aberrant HLA expression patterns on HNSCC tumour cells and this study focused on the allelic polymorphism of HLA genes and the MHC class I chain related gene A...
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