Article
RFLP characterization of the upstream regulatory region of the HLA-DQA1 gene.
Tissue antigens - 1 Feb 1994
Maffei A, Reed E F, McManus P, Guardiola J, Suciu Foca N
Abstract excerpt
We have performed population and family studies of the distribution of DNA restriction length polymorphisms (RFLPs) in the 5' region of the HLA-DQA1 gene using a probe which corresponds to a sequence of the 5' flanking region of HLA-DQA1. Southern analysis detected four polymorphic fragments (X1,...
Topics
- Alleles
- Blotting, Southern
- Chromosome Mapping
- DNA
- Family Health
- Gene Expression Regulation
- Gene Frequency
- Genetic Linkage
- HLA-DQ Antigens
- HLA-DQ alpha-Chains
- Haplotypes
- Heterozygote
- Homozygote
- Humans
- Polymorphism, Genetic
- Polymorphism, Restriction Fragment Length
