Article
RFLP characterization of the upstream regulatory region of the HLA-DQA1 gene.
Tissue antigens - 1 Feb 1994
Maffei A, Reed E F, McManus P, Guardiola J, Suciu Foca N
Abstract excerpt
We have performed population and family studies of the distribution of DNA restriction length polymorphisms (RFLPs) in the 5' region of the HLA-DQA1 gene using a probe which corresponds to a sequence of the 5' flanking region of HLA-DQA1. Southern analysis detected four polymorphic fragments (X1, X2, X3 and X4) with XbaI and three fragments (E1, E2 and E3) with EcoRI. Family segregation studies showed that these...
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