Article
Infrequent loss of heterozygosity at adenomatous polyposis coli gene locus in Indian oral cancers.
Cancer letters - 1 Sept 2000
Tandle A, Sanghavi V, Saranath D
Abstract excerpt
We have investigated loss of heterozygosity (LOH) of the adenomatous polyposis coli (APC) tumor suppressor gene using polymerase chain reaction (PCR)-restriction fragment length polymorphism (RFLP) in 86 untreated oral cancer patients, using matched oral cancer tissue and corresponding peripheral blood cell (PBC) DNA samples. PBC from 70 normal healthy individuals, were also analyzed for allelic distribution of...
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