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Article

An efficient genetic screen in Drosophila to identify nuclear-encoded genes with mitochondrial function.

Genetics - 1 Sept 2006

Liao T S Vivian, Call Gerald B, Guptan Preeta, Cespedes Albert, Marshall Jamie, Yackle Kevin, Owusu-Ansah Edward, Mandal Sudip, Fang Q Angela, Goodstein Gelsey L, Kim William, Banerjee Utpal

Abstract excerpt

We conducted a screen for glossy-eye flies that fail to incorporate BrdU in the third larval instar eye disc but exhibit normal neuronal differentiation and isolated 23 complementation groups of mutants. These same phenotypes were previously seen in mutants for cytochrome c oxidase subunit Va. We have molecularly characterized six complementation groups and, surprisingly, each encodes a mitochondrial protein....

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Identifiers

PMID: 16849596
DOI: 10.1534/genetics.106.061705
PMCID: PMC1569793

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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