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Article

A novel strategy for identifying mutations that sensitize Drosophila eye development to caffeine and hydroxyurea.

Genome - 1 Nov 2006

Silva E A, Lee B J, Caceres L S, Renouf D, Vilay B R, Yu O, Bradley J A, Campbell S D

Abstract excerpt

This report describes a novel strategy for isolating Drosophila mutants with conditional eye phenotypes that should be generally applicable for identifying genes required for cellular responses to specific drugs. To test the strategy, we screened 3 of the 5 major chromosome arms for hydroxyurea- and (or) caffeine-sensitive (huc) mutants, and isolated mutations affecting 5 different complementation groups. Most of...

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PMID: 17426757
DOI: 10.1139/g06-098

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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