A direct screen identifies new flight muscle mutants on the Drosophila second chromosome.

doi:10.1093/genetics/153.1.261

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Article

A direct screen identifies new flight muscle mutants on the Drosophila second chromosome.

Genetics - 1 Sept 1999

Nongthomba U, Ramachandra N B

Abstract excerpt

An ethyl methanesulfonate mutagenesis of Drosophila melanogaster was undertaken, and >3000 mutagenized second chromosomes were generated. More than 800 homozygous viable lines were established, and adults were screened directly under polarized light for muscle defects. A total of 16 mutant strains in which the indirect flight muscles were reduced in volume or disorganized or were otherwise abnormal were...

Topics

Animals
Chromosome Mapping
Chromosomes
Drosophila
Female
Fertility
Flight, Animal
Genes, Insect
Genes, Lethal
Genes, Recessive
Genetic Complementation Test
Male
Muscle Development
Muscles
Mutation
Myosin Heavy Chains
Pupa
Terminology as Topic

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Identifiers

PMID: 10471711
DOI: 10.1093/genetics/153.1.261
PMCID: PMC1460746

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