Article
Two-color in vivo imaging of photoreceptor apoptosis and development in Drosophila.
Developmental biology - 1 Mar 2011
Gambis Alexis, Dourlen Pierre, Steller Hermann, Mollereau Bertrand
Abstract excerpt
We report a new two-color fluorescent imaging system to visualize the mosaic adult photoreceptor neurons (PRs) in real-time. Using this method, we examined a collection of 434 mutants and identified genes required for PR survival, planar cell polarity (PCP), patterning and differentiation. We could track the progression of PR degeneration in living flies. By introducing the expression of p35, a caspase inhibitor,...
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