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Article

T-bet deficiency facilitates airway colonization by Mycoplasma pulmonis in a murine model of asthma.

Journal of immunology (Baltimore, Md. : 1950) - 1 Aug 2006

Bakshi Chandra Shekhar, Malik Meenakshi, Carrico Pauline M, Sellati Timothy J

Abstract excerpt

Epidemiological and clinical evidence suggest a correlation between asthma and infection with atypical bacterial respiratory pathogens. However, the cellular and molecular underpinnings of this correlation remain unclear. Using the T-bet-deficient (T-bet(-/-)) murine model of asthma and the natural murine pathogen Mycoplasma pulmonis, we provide a mechanistic explanation for this correlation. In this study, we...

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Identifiers

PMID: 16849489
DOI: 10.4049/jimmunol.177.3.1786

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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