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Article

Novel Therapies for Pneumonia-Associated Severe Asthma Phenotypes.

Trends in molecular medicine - 1 Nov 2020

Papanicolaou Angelica, Wang Hao, Satzke Catherine, Vlahos Ross, Wilson Nick, Bozinovski Steven

Abstract excerpt

Distinct asthma phenotypes are emerging from well-defined cohort studies and appear to be associated with a history of pneumonia. Asthmatics are more susceptible to infections caused by Streptococcus pneumoniae; however, the mechanisms that underlie defective immunity to this pathogen are still being elucidated. Here, we discuss how alternatively activated macrophages (AAMs) in asthmatics are defective in...

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Identifiers

PMID: 32828703
DOI: 10.1016/j.molmed.2020.07.006

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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