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Article

Frequencies of BRAF and NRAS mutations are different in histological types and sites of origin of cutaneous melanoma: a meta-analysis.

The British journal of dermatology - 1 Apr 2011

Lee J-H, Choi J-W, Kim Y-S

Abstract excerpt

BACKGROUND: There have been conflicting data regarding the prevalence and clinicopathological characteristics of BRAF and NRAS mutations in primary cutaneous melanoma. OBJECTIVES: To solve this controversy, this study used a meta-analysis to evaluate the frequencies of BRAF and NRAS mutations, and the relationship between these mutations and clinicopathological parameters of cutaneous melanoma. METHODS: Data from...

Topics

Age Factors
DNA Mutational Analysis
Female
Gene Frequency
Genes, ras
Humans
Male
Melanoma
Mutation
Odds Ratio
Proto-Oncogene Proteins B-raf
Sex Factors

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Skin Neoplasms

Source

Identifiers

PMID: 21166657
DOI: 10.1111/j.1365-2133.2010.10185.x

Genes

BRAF
NRAS

Provenance

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