Article
Frequencies of BRAF and NRAS mutations are different in histological types and sites of origin of cutaneous melanoma: a meta-analysis.
The British journal of dermatology - 1 Apr 2011
Lee J-H, Choi J-W, Kim Y-S
Abstract excerpt
BACKGROUND: There have been conflicting data regarding the prevalence and clinicopathological characteristics of BRAF and NRAS mutations in primary cutaneous melanoma. OBJECTIVES: To solve this controversy, this study used a meta-analysis to evaluate the frequencies of BRAF and NRAS mutations, and the relationship between these mutations and clinicopathological parameters of cutaneous melanoma. METHODS: Data from...
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