White-spotting mutations affect the regenerative differentiation of testicular germ cells: demonstration by experimental cryptorchidism and its surgical reversal.

doi:10.1095/biolreprod45.4.642

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Article

White-spotting mutations affect the regenerative differentiation of testicular germ cells: demonstration by experimental cryptorchidism and its surgical reversal.

Biology of reproduction - 1 Oct 1991

Koshimizu U, Sawada K, Tajima Y, Watanabe D, Nishimune Y

Abstract excerpt

The effect of white-spotting (W) mutations on differentiation of testicular germ cells was investigated by using experimental cryptorchidism and its surgical reversal. All mutant mice used in this study (Wv/+, Wsh/+, Wf/+ and Wf/Wf) showed normal fertility and well-ordered spermatogenesis, as in...

Topics

Animals
Cell Differentiation
Cryptorchidism
Male
Mice
Mice, Inbred C57BL
Mice, Mutant Strains
Mutation
Proto-Oncogenes
Spermatogenesis
Testis

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