An extreme bias in the germ line of XY C57BL/6<->XY FVB/N chimaeric mice.

doi:10.1530/rep.0.1240377

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Back to search

Article

An extreme bias in the germ line of XY C57BL/6<->XY FVB/N chimaeric mice.

Reproduction (Cambridge, England) - 1 Sept 2002

MacGregor G R

Abstract excerpt

Chimaeric analysis is a powerful method to address questions about the cell-autonomous nature of defects in spermatogenesis. Symplastic spermatids (sys) mice have a recessive mutation that causes male sterility due to an arrest in germ-cell development during spermiogenesis. Chimaeric mice were generated by aggregation of eight-cell embryos from sys (FVB/N genetic background) and wild-type C57BL/6 (B6) mice to...

Topics

Animals
Blotting, Southern
Chimera
Female
Fertility
Genotype
Infertility, Male
Male
Mice
Mice, Inbred C57BL
Mutation
Phenotype
Spermatogenesis
Spermatozoa
Testis

Source

Open in PubMed Open full text

Identifiers

PMID: 12201811
DOI: 10.1530/rep.0.1240377
PMCID: PMC3049803

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026.

Community interpretation

Discuss the evidence

Ask a question, add context or challenge an interpretation. Community activity is separate from scientific evidence strength.

discussions

replies

Citations encouraged

Claims remain attributable.

No discussion yet

Be the first to add a careful, cited interpretation.

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics