Article
Degeneration of Sertoli and spermatogenic cells in homozygous and heterozygous weaver mice.
Journal of neurogenetics - 1 Feb 1995
Verina T, Tang X, Fitzpatrick L, Norton J, Vogelweid C, Ghetti B
Abstract excerpt
In the neurological mutant mouse weaver (wv/wv), the majority of males are infertile due to hypospermatogenesis. Heterozygous weaver mice (wv/+) cease mating successfully when males reach an average age of 3.5 months. The contents of epididymal fluid were scored for the number of sperm and sperm motility in wv/wv, wv/+ and controls. Testes were examined in mice of the three genotypes at various ages using light...
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