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Article

Allelic variation in the TNF-beta gene does not explain the low TNF-beta response in patients with primary biliary cirrhosis.

Scandinavian journal of immunology - 1 Dec 1991

Messer G, Spengler U, Jung M C, Honold G, Eisenburg J, Scholz S, Albert E D, Pape G R, Riethmüller G, Weiss E H

Abstract excerpt

Autoimmune disorders in humans are often associated with particular alleles of major histocompatibility genes. However, the chronic inflammatory liver disease primary biliary cirrhosis (PBC) has not been found to be correlated with certain haplotypes so far. Interestingly, an impaired production...

Topics

Alleles
Histocompatibility Antigens Class I
Histocompatibility Antigens Class II
Humans
Liver Cirrhosis, Biliary
Lymphotoxin-alpha
Polymorphism, Restriction Fragment Length

Source

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Identifiers

PMID: 1684248
DOI: 10.1111/j.1365-3083.1991.tb01598.x

Genes

TNF

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026. Prepared record publication-1684248-2026-08-30.1. Manifest publication-graph-cohort-2026-08-30.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 30 Aug 2026.

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