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Article

Tumour necrosis factor gene polymorphisms in lymphoproliferative disease.

Leukemia & lymphoma - 1 Aug 2000

Mainou-Fowler T, Dickinson A M, Taylor P R, Mounter P, Jack F, Proctor S J, Nordon J, Middleton P G

Abstract excerpt

Tumour necrosis factor (TNF) alpha is involved in the pathogenesis of established lymphoproliferative disease. Serum levels of TNFalpha and its soluble receptors are above normal values in B-cell chronic lymphocytic leukaemia (B-CLL) and they are valuable prognostic markers in lymphoma patients. The production of TNFalpha is genetically controlled. Altered synthesis of TNFalpha has been associated with...

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Source

Identifiers

PMID: 10953976
DOI: 10.3109/10428190009059274

Genes

TNF
LTB

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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