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Article

Vascular effects of a common gene variant of extracellular superoxide dismutase in heart failure.

American journal of physiology. Heart and circulatory physiology - 1 Aug 2006

Iida Shinichiro, Chu Yi, Weiss Robert M, Kang Yu Ming, Faraci Frank M, Heistad Donald D

Abstract excerpt

A common gene variant of human extracellular superoxide dismutase (ecSOD), in approximately 5% of humans, is associated with increased risk of ischemic heart disease. The purpose of this study was to examine vascular effects of ecSOD with effects of the ecSOD variant (ecSOD(R213G)) in rats with heart failure. Seven weeks after coronary artery ligation, we studied rats with heart failure and sham-operated rats....

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Identifiers

PMID: 16840738
DOI: 10.1152/ajpheart.00080.2006

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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