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Article

Estradiol improves cardiovascular function through up-regulation of SOD2 on vascular wall

1 Jan 2014

Abstract excerpt

Epidemiological studies have shown that estrogens have protective effects in cardiovascular diseases, even though the results from human clinical trials remain controversial, while most of the animal experiments confirmed this effect, but the detailed mechanism remains unclear. In this study, we found that estradiol (E2) treatment significantly increases the expression of mitochondrial superoxide dismutase (SOD2)...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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PMID: 25462070
DOI: 10.1016/j.redox.2014.11.001

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