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Article

Nitric oxide synthase gene therapy: progress and prospects

25 May 2009

Abstract excerpt

NOS gene therapy has been the focus of extensive research as dysfunction of this enzyme has been implicated in several cardiovascular diseases. Research has concentrated on comparing the effect of gene delivery of NOS isoforms (eNOS, iNOS and nNOS) in healthy and diseased animal models on intimal hyperplasia, restenosis, vascular tone and ischemia-reperfusion injury. Most results demonstrate therapeutic benefits...

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PMID: 19463074
DOI: 10.1517/14712590903002047

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