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Article

Gene transfer of extracellular superoxide dismutase reduces arterial pressure in spontaneously hypertensive rats: role of heparin-binding domain.

Circulation research - 7 Mar 2003

Chu Yi, Iida Shinichiro, Lund Donald D, Weiss Robert M, DiBona Gerald F, Watanabe Yoshimasa, Faraci Frank M, Heistad Donald D

Abstract excerpt

Oxidative stress may contribute to hypertension. The goals of this study were to determine whether extracellular superoxide dismutase (ECSOD) reduces arterial pressure in spontaneously hypertensive rats (SHR) and whether its heparin-binding domain (HBD), which is responsible for cellular binding,...

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Source

Identifiers

PMID: 12600899
DOI: 10.1161/01.RES.0000057755.02845.F9

Genes

HBD

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-12600899-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

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