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Epstein-Barr virus lytic reactivation regulation and its pathogenic role in carcinogenesis

1 Jan 2016

Abstract excerpt

Epstein-Barr virus (EBV) has been associated with several types of human cancers. In the host, EBV can establish two alternative modes of life cycle, known as latent or lytic and the switch from latency to the lytic cycle is known as EBV reactivation. Although EBV in cancer cells is found mostly in latency, a small number of lytically-infected cells promote carcinogenesis through the release of growth factors and...

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PMID: 27877083
DOI: 10.7150/ijbs.16564

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