Article
Crystal structure of d(gcGXGAgc) with X=G: a mutation at X is possible to occur in a base-intercalated duplex for multiplex formation.
Nucleosides, nucleotides & nucleic acids - 1 Jan 2006
Kondo Jiro, Ciengshin Tanashaya, Juan Ella Czarina Magat, Sato Yoshiteru, Mitomi Kenta, Shimizu Satoru, Takénaka Akio
Abstract excerpt
DNA fragments with the sequences d(gcGX[Y]n Agc) (n=1, X=A, and Y=A, T, or G)form base-intercalated duplexes, which is a basic unit for formation of multiplexes such as octaplex and hexaplex. To examine the stability of multiplexes, a DNA with X=Y=G and n=1 was crystallized under conditions different from those of the previously determined sequences, and its crystal structure has been determined. The two strands...
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