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Article

Chronic lymphoproliferative disorder with regulatory T-cell phenotype.

American journal of hematology - 1 Sept 2006

Kikuchi Tomoko, Katayama Yoshio, Kubonishi Shiro, Watanabe Toshiyuki, Watanabe Yukari, Matsuoka Ken-ichi, Maeda Yoshinobu, Namba Noriko, Masunari Taro, Nasu Ryusuke, Ikeda Kazuma, Tanimoto Mitsune

Abstract excerpt

We report a case of T-cell chronic lymphoproliferative disorder (CLPD) that shows neither features of T-cell prolymphocytic leukemia nor disease progression for more than 34 months. Flow cytometric analyses of the lymphocytes revealed high expression of CD4 and CD25. Up-regulation of Foxp3, a master regulatory gene for developmental differentiation of regulatory T cells (Treg), was confirmed at mRNA and protein...

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Identifiers

PMID: 16838340
DOI: 10.1002/ajh.20688

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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