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Article

FOXP3+CD25- tumor cells with regulatory function in Sézary syndrome.

The Journal of investigative dermatology - 1 Dec 2009

Heid Julia B, Schmidt Angelika, Oberle Nina, Goerdt Sergij, Krammer Peter H, Suri-Payer Elisabeth, Klemke Claus-Detlev

Abstract excerpt

Cutaneous T-cell lymphoma (CTCL) has been suggested by in vitro experiments to represent a malignant CD4+ T-cell proliferation with a regulatory T-cell (Treg) phenotype (CD4+CD25+FOXP3+). We investigated percentages of FOXP3+ and CD25+ cells in the blood of 15 Sézary, 14 mycosis fungoides (MF), and 10 psoriasis (Pso) patients and 20 normal healthy donors (NHDs). We found similar numbers of FOXP3+ cells in MF...

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Source

Identifiers

PMID: 19626037
DOI: 10.1038/jid.2009.175

Genes

FOXP3

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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