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Article

A novel HIV-1 isolate containing alterations affecting the NF-kappa B element.

Virology - 1 Mar 1991

Englund G, Hoggan M D, Theodore T S, Martin M A

Abstract excerpt

Three molecular clones of HIV-1, derived from a single isolate (AL1), exhibited distinct replicative and cytopathic properties during propagation in a human T cell line. The phenotypic differences observed were attributable, in large part, to changes affecting the viral LTR. Nucleotide sequence and PCR analyses demonstrated the presence of novel duplications or deletions involving the NF-kappa B motif. These...

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PMID: 1994572
DOI: 10.1016/0042-6822(91)90479-u

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CAT

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