Article
Exploring the association of glyceraldehyde-3-phosphate dehydrogenase gene and Alzheimer disease.
Neurology - 11 Jul 2006
Lin P I, Martin E R, Bronson P G, Browning-Large C, Small G W, Schmechel D E, Welsh-Bohmer K A, Haines J L, Gilbert J R, Pericak-Vance M A
Abstract excerpt
BACKGROUND: Previous linkage studies have shown that chromosome 12 harbors susceptibility genes for late-onset Alzheimer disease (LOAD). However, association studies of several candidate genes on this chromosome region have produced ambiguous results. A recent study reported the association between the glyceraldehyde-3-phosphate dehydrogenase (GAPD) gene on chromosome 12p and the risk of LOAD. METHODS: The...
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