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Article

Complex dynamics and stability of resistance to antimalarial drugs

23 Jan 2006

Abstract excerpt

A succession of antimalarial drugs has been deployed to treat human falciparum malaria but each has, in turn, been nullified by the spread of drug resistance. The consensus view has always been that, once present, resistance will inevitably rapidly increase to 100%. However, recent field evidence has shown this is not inevitable, and that drug resistance may initially spread and then stabilize at relatively low...

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PMID: 16426485
DOI: 10.1017/s0031182005009790

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