Article
Expression and function of NPSR1/GPRA in the lung before and after induction of asthma-like disease.
American journal of physiology. Lung cellular and molecular physiology - 1 Nov 2006
Allen Irving C, Pace Amy J, Jania Leigh A, Ledford Julie G, Latour Anne M, Snouwaert John N, Bernier Virginie, Stocco Rino, Therien Alex G, Koller Beverly H
Abstract excerpt
A genetic contribution to asthma susceptibility is well recognized, and linkage studies have identified a large number of genes associated with asthma pathogenesis. Recently, a locus encoding a seven-transmembrane protein was shown to be associated with asthma in founder populations. The expression of the protein GPRA (G protein-coupled receptor for asthma susceptibility) in human airway epithelia and smooth...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.