Article
Genetic differences in airway smooth muscle function.
Proceedings of the American Thoracic Society - 1 Jan 2008
Martin James G, Jo Taisuke
Abstract excerpt
The genetic basis for airway smooth muscle properties is poorly explored. Contraction and relaxation are altered in asthmatic airway smooth muscle, but the basis for the alterations and the role that muscle-specific susceptibility genes may play is largely unexplored. Alterations in the beta-adrenergic receptor, signaling pathways affecting inositol phosphate metabolism, adenylyl and guanylyl cyclase activity,...
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