Article
Mapping genes for asthma and psoriasis.
Novartis Foundation symposium - 1 Jan 2005
Kere Juha
Abstract excerpt
A property of susceptibility genes for complex diseases is their reduced penetrance, due to the influences of other genes, the environment, or stochastic events. With this in mind, it is possible to devise population genetic strategies and statistical methods to allow their positional cloning. The identification of the relevant effector gene in an implicated locus may provide further challenges and require...
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