[Resistance to anticancer drugs].

Article

[Resistance to anticancer drugs].

Presse medicale (Paris, France : 1983) - 16 Nov 1996

Bénard J, Rixe O

Abstract excerpt

Due to inefficacy of chemotherapy in several cancers, chemoresistance mechanisms which are intrinsic to tumor cells have been extensively described in human cancer cell lines. Detoxifying mechanisms including active efflux pumps (P-gp, MRP or LRP) and/or drug inactivation (glutathione) as well as...

Topics

DNA Repair
Drug Resistance, Multiple
Drug Resistance, Neoplasm
Forecasting
Humans
Phenotype

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