Article
Hypoxic induction of human visfatin gene is directly mediated by hypoxia-inducible factor-1.
FEBS letters - 24 Jul 2006
Bae Soo-Kyung, Kim Su-Ryun, Kim Jong Gab, Kim Jee Yeon, Koo Tae Hyeon, Jang Hye-Ock, Yun Il, Yoo Mi-Ae, Bae Moon-Kyoung
Abstract excerpt
Visfatin has been originally identified as a growth factor for early stage B cells and recently known as an adipokine. Here, we report that hypoxia induces the visfatin mRNA and protein levels in MCF7 breast cancer cells. We also demonstrate that induction of visfatin gene is regulated by hypoxia...
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