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Article

Visfatin in adipocytes is upregulated by hypoxia through HIF1alpha-dependent mechanism.

Biochemical and biophysical research communications - 27 Oct 2006

Segawa Katsumori, Fukuhara Atsunori, Hosogai Naomi, Morita Kentaro, Okuno Yosuke, Tanaka Masaki, Nakagawa Yasuhiko, Kihara Shinji, Funahashi Tohru, Komuro Ryutaro, Matsuda Morihiro, Shimomura Iichiro

Abstract excerpt

Obesity is associated with metabolic disorders, such as insulin resistance. Visfatin is an adipose-derived secretory factor to exert insulin-mimetic effects. Plasma visfatin levels and mRNA levels of visfatin in adipose tissues are increased in obesity. However, the mechanism that mediates induction of visfatin mRNA in adipose tissue of obesity remains unknown. Recent studies have reported that fat tissue is...

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Identifiers

PMID: 16970912
DOI: 10.1016/j.bbrc.2006.07.083

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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