Article
In-vitro function of upstream visfatin polymorphisms that are associated with adverse cardiometabolic parameters in obese children.
BMC genomics - 25 Nov 2016
Ooi Delicia Shu Qin, Ong Siong Gim, Heng Chew Kiat, Loke Kah Yin, Lee Yung Seng
Abstract excerpt
BACKGROUND: Visfatin is an adipokine associated with glucose and lipid metabolism. We previously reported two visfatin upstream single nucleotide polymorphisms (SNPs), c.-3187G > A (rs11977021) and c.-1537C > T (rs61330082), which were in perfect linkage disequilibrium, in a Singaporean cohort of severely obese children and are associated with visfatin level and adverse cardiometabolic parameters. We aim to...
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