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The ETS Factor Myeloid Elf-1-Like Factor (MEF)/Elf4 Is Transcriptionally and Functionally Activated by Hypoxia

1 Jan 2016

Abstract excerpt

Hypoxia-inducible factor (HIF)-1α is a transcription factor belonging to the HIF family that is activated in mammalian cells during conditions of low oxygen tension or hypoxia to induce an adaptive response and promote cell survival. Some of the genes targeted by HIF-1α are important for angiogenesis and proliferation. Here, we found that the E26 transformation-specific (ETS) transcription factor myeloid...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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PMID: 27040637
DOI: 10.1248/bpb.b15-00796

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