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Article

Ligand-specific sequential regulation of transcription factors for differentiation of MCF-7 cells.

BMC genomics - 20 Nov 2009

Saeki Yuko, Endo Takaho, Ide Kaori, Nagashima Takeshi, Yumoto Noriko, Toyoda Tetsuro, Suzuki Harukazu, Hayashizaki Yoshihide, Sakaki Yoshiyuki, Okada-Hatakeyama Mariko

Abstract excerpt

BACKGROUND: Sharing a common ErbB/HER receptor signaling pathway, heregulin (HRG) induces differentiation of MCF-7 human breast cancer cells while epidermal growth factor (EGF) elicits proliferation. Although cell fates resulting from action of the aforementioned ligands completely different, the...

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Share to Cell Differentiation
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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 19925682
DOI: 10.1186/1471-2164-10-545
PMCID: PMC2785842

Genes

FHL2
HRG
FOS
EGF
EGR4

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-19925682-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

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Ligand-specific sequential regulation of transcription factors for differentiation of MCF-7 cells.PMID 19925682Read ↗

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