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Article

The death domain kinase RIP has an important role in DNA damage-induced, p53-independent cell death.

The Journal of biological chemistry - 1 Sept 2006

Hur Gang Min, Kim You-Sun, Won Minho, Choksi Swati, Liu Zheng-gang

Abstract excerpt

Tumor suppressor p53 plays a critical role in cellular responses, such as cell cycle arrest and apoptosis following DNA damage. DNA damage-induced cell death can be mediated by a p53-dependent or p53-independent pathway. Although p53-mediated apoptosis has been well documented, little is known about the signaling components of p53-independent cell death. Here we report that the death domain kinase, RIP...

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Identifiers

PMID: 16825191
DOI: 10.1074/jbc.M605577200

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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