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Article

The serine threonine kinase RIP3: lost and found

30 Jun 2015

Abstract excerpt

Receptor-interacting protein kinase-3 (RIP3, or RIPK3) is an essential protein in the "programmed", or "regulated" necrosis cell death pathway that is activated in response to death receptor ligands and other types of cellular stress. Programmed necrotic cell death is distinguished from its apoptotic counterpart in that it is not characterized by the activation of caspases; unlike apoptosis, programmed necrosis...

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Identifiers

PMID: 25858093
DOI: 10.5483/bmbrep.2015.48.6.068

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