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Article

Variation in T-lymphocyte activation and susceptibility to SIVPBj-14-induced acute death in macaques.

Journal of medical primatology - 1 Jun 1991

Rosenberg Y J, White B D, Papermaster S F, Zack P, Jarling P B, Eddy G A, Burke D S, Lewis M G

Abstract excerpt

In contrast to pig-tailed and cynomolgus macaques, which die in 6-10 days following infection with the SIV-PBj-14 isolate, only about 50% of rhesus succumbed to rapid disease. Using a CD45RA MAb that delineates memory (CD45RAlo), naive (CD45RAmed) and "activated" (CD45RAhi) T-cell subsets, it was seen that PBMC from pig-tailed and cynomolgus monkeys, unlike rhesus, have reduced CD4/CD8 ratios and a skewing of T...

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PMID: 1682498

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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