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Article

Acute lymphoid changes and ongoing immune activation in SIV infection.

Journal of acquired immune deficiency syndromes - 1 Jan 1992

Popov J, McGraw T, Hofmann B, Vowels B, Shum A, Nishanian P, Fahey J L

Abstract excerpt

Two features of simian immunodeficiency virus (SIV) infection are emphasized: a transitory decrease in CD4 T cells in the first 2 weeks of infection followed by CD8 T-cell rise, and immune cell activation occurring by 4 weeks and persisting throughout the illness. The short-term changes included a fall in CD4 T cells by 2 weeks with partial recovery by 4 weeks and a CD8 rise that starts at 2 weeks. Subsequent...

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PMID: 1548574

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

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