Article
Acute lymphoid changes and ongoing immune activation in SIV infection.
Journal of acquired immune deficiency syndromes - 1 Jan 1992
Popov J, McGraw T, Hofmann B, Vowels B, Shum A, Nishanian P, Fahey J L
Abstract excerpt
Two features of simian immunodeficiency virus (SIV) infection are emphasized: a transitory decrease in CD4 T cells in the first 2 weeks of infection followed by CD8 T-cell rise, and immune cell activation occurring by 4 weeks and persisting throughout the illness. The short-term changes included a fall in CD4 T cells by 2 weeks with partial recovery by 4 weeks and a CD8 rise that starts at 2 weeks. Subsequent...
Topics
- Animals
- Antibodies, Viral
- Biomarkers
- Biopterins
- Longitudinal Studies
- Lymphocyte Activation
- Lymphocyte Subsets
- Macaca mulatta
- Neopterin
- Phenotype
- Simian Acquired Immunodeficiency Syndrome