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Comparison of Influenza and SIV Specific CD8 T Cell Responses in Macaques

5 Mar 2012

Abstract excerpt

Macaques are a potentially useful non-human primate model to compare memory T-cell immunity to acute virus pathogens such as influenza virus and effector T-cell responses to chronic viral pathogens such as SIV. However, immunological reagents to study influenza CD8(+) T-cell responses in the macaque model are limited. We recently developed an influenza-SIV vaccination model of pigtail macaques (Macaca nemestrina)...

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PMID: 22403659
DOI: 10.1371/journal.pone.0032431

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