Article
Loss of the SIVsmmPBj14 phenotype and nef genotype during long-term survival of macaques infected by mucosal routes.
Virology - 31 Mar 1997
Schwiebert R S, Tao B, Fultz P N
Abstract excerpt
The ability of the simian immunodeficiency virus SIVsmmPBj14 (SIV-PBj14) to activate and induce proliferation of quiescent peripheral blood lymphocytes from macaques is an in vitro correlate of its acutely lethal in vivo phenotype. SIV-PBj14 differs from other SIV strains by encoding tyrosine at...
Topics
- Acute Disease
- Amino Acid Sequence
- Animals
- Female
- Gene Products, nef
- Genotype
- Macaca
- Male
- Molecular Sequence Data
- Mucous Membrane
- Phenotype
- Simian Acquired Immunodeficiency Syndrome