Article

Adenosine tips the pathogenic Th1 and Th17 responses in experimental autoimmune uveitis (EAU)

2020-07-06

Abstract excerpt

Various pathological conditions are accompanied by ATP release from the intracellular to the extracellular compartment, where it degrades into adenosine and modulates immune responses. Previous studies concluded that both ATP and its degradation product adenosine are important immune-regulatory molecules; ATP acted as a danger signal that promotes immune responses, but adenosine’s effect was inhibitory. In this st...

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Literature Corpus work: 8588b74a-ac36-5827-a2fe-c8f1d73b8576
DOI: 10.1101/2020.07.06.189183

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