Article
Single-nucleotide polymorphisms in adiponectin, AdipoR1, and AdipoR2 genes: insulin resistance and type 2 diabetes mellitus candidate genes.
American journal of therapeutics - 1 Jan 2000
Bermúdez Valmore J, Rojas Edward, Toledo Alexandra, Rodríguez-Molina Daloha, Vega Keren, Suárez Luis, Pacheco Maikol, Canelón Roger, Arráiz Nailet, Rojas Joselyn, Velasco Manuel
Abstract excerpt
It has already been a decade and a half since the discovery of adiponectin and its role as an insulin sensitizer and only 7 years since its receptors, AdipoR1 and AdipoR2, were described. A single-nucleotide polymorphism (SNP) is a DNA sequence variation that affects only one nucleotide; it may vary from one population to another with different predisposing factors to diseases and other ailments. Once some of the...
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