Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Is multidrug resistance relevant in breast cancer?

European journal of surgical oncology : the journal of the European Society of Surgical Oncology and the British Association of Surgical Oncology - 1 Oct 1991

Wishart G C, Kaye S B

Abstract excerpt

The multidrug resistance phenotype is associated with expression of P-glycoprotein (P-gp), an energy-dependent drug efflux pump. P-gp is expressed in several clinically resistant human cancers. This article discusses the evidence that P-gp expression may be implicated in the development of clinical drug resistance in patients with breast cancer.

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Antineoplastic Agents
Share to ATP Binding Cassette Transporter, Subfamily B, Member 1

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Breast Neoplasms

Share to Drug Resistance

Share to Membrane Glycoproteins

Share to Neoplasm Proteins

Share to Phenotype

Source

Identifiers

PMID: 1682166

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Is multidrug resistance relevant in breast cancer?PMID 1682166Read ↗

ATP binding cassette transporters and drug resistance in breast cancer.Semantic proximity Read ↗

Multidrug Resistance/P-Glycoprotein and Breast Cancer: Review and Meta-AnalysisSemantic proximity Read ↗

Multidrug Resistance in Breast Cancer: From<i>In Vitro</i>Models to Clinical StudiesSemantic proximity Read ↗

Impact of breast cancer resistance protein on cancer treatment outcomes.Semantic proximity Read ↗

Drug transporters: recent advances concerning BCRP and tyrosine kinase inhibitorsSemantic proximity Read ↗

Breast cancer resistance protein (BCRP/ABCG2): its role in multidrug resistance and regulation of its gene expressionSemantic proximity Read ↗

ABC transporters in breast cancer: their roles in multidrug resistance and beyondSemantic proximity Read ↗

The Role of Multidrug Resistance Efflux Pumps in Cancer: Revisiting a JNCI Publication Exploring Expression of the MDR1 (P-glycoprotein) GeneSemantic proximity Read ↗

Relevance of multidrug resistance in the age of targeted therapy.Semantic proximity Read ↗

Pleiotropic Roles of ABC Transporters in Breast CancerSemantic proximity Read ↗

Clinical significance of P-glycoprotein in multidrug resistance malignancies [editorial] [see comments]Semantic proximity Read ↗

Clinical significance of P-glycoprotein in multidrug resistance malignancies [editorial] [see comments]Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.