Article
GlpD and PlsB participate in persister cell formation in Escherichia coli.
Journal of bacteriology - 1 Jul 2006
Spoering Amy L, Vulic Marin, Lewis Kim
Abstract excerpt
Bacterial populations produce dormant persister cells that are resistant to killing by all antibiotics currently in use, a phenomenon known as multidrug tolerance (MDT). Persisters are phenotypic variants of the wild type and are largely responsible for MDT of biofilms and stationary populations. We recently showed that a hipBA toxin/antitoxin locus is part of the MDT mechanism in Escherichia coli. In an effort...
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