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Article

Highly efficient generation of signal transduction knockout mutants using a fungal strain deficient in the mammalian ku70 ortholog.

Gene - 15 Aug 2006

Pöggeler Stefanie, Kück Ulrich

Abstract excerpt

Targeted gene replacement via homologous recombination is a routinely used approach to elucidate the function of unknown genes. Integration of exogenous DNA in the genomic DNA requires the action of double-strand repair mechanisms. The filamentous ascomycete Sordaria macrospora is a model system for studying fruiting body development in fungi. In contrast to the budding yeast Saccharomyces cerevisiae, but similar...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 16814491
DOI: 10.1016/j.gene.2006.03.020

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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