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Article

Screening of alpha-1-antitrypsin gene by denaturing gradient gel electrophoresis (DGGE).

Journal of biochemical and biophysical methods - 31 Oct 2006

Ljujic Mila, Nikolic Aleksandra, Divac Aleksandra, Djordjevic Valentina, Radojkovic Dragica

Abstract excerpt

Alpha-1-antitrypsin (AAT) is a serine protease inhibitor whose deficiency could cause emphysema and liver disease and, as recently described, could be a risk factor for lung cancer development. Alpha-1-antitrypsin inhibits a variety of proteases but its primary target is neutrophil elastase, an extracellular endopeptidase capable of degrading most protein components of the extracellular matrix. Inhibition of...

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Identifiers

PMID: 16814390
DOI: 10.1016/j.jbbm.2006.05.005

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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