Article
Single nucleotide polymorphism genotyping in MMP genes: the 5' nuclease assay.
Methods in molecular biology (Clifton, N.J.) - 1 Jan 2010
Laxton Ross, Ye Shu
Abstract excerpt
Many molecular genetic studies of human diseases involve determining the genotypes for single nucleotide polymorphisms. This chapter summarises a number of different techniques for the single nucleotide polymorphism genotyping which can be applied to MMP genes. The chapter also provides a protocol and technical notes for the 5'-nuclease assay, one of the most commonly used genotyping techniques.
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