Article
Detection of the Bcl I polymorphism of the glucocorticoid receptor gene by single-tube allele-specific polymerase chain reaction.
The Journal of steroid biochemistry and molecular biology - 1 Aug 2006
Gergics Peter, Patocs Attila, Majnik Judit, Balogh Katalin, Szappanos Agnes, Toth Miklos, Racz Karoly
Abstract excerpt
The Bcl I polymorphism of the glucocorticoid receptor gene, recently identified as an intronic C to G change 646 nucleotides downstream of exon 2, has been associated with increased sensitivity to glucocorticoids and its potential relevance in metabolic disturbances and in various disorders has been extensively investigated. In the present study, we designed a single-tube allele-specific polymerase chain reaction...
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