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Article

Deficiency of Adenomatous Polyposis Coli protein in sporadic colorectal adenomas and its associations with clinical phenotype and histology.

World journal of gastroenterology - 28 Jun 2006

Bortlik Martin, Vitkova Ivana, Papezova Martina, Kohoutova Milada, Novotny Ales, Adamec Stanislav, Chalupna Petra, Lukas Milan

Abstract excerpt

AIM: To evaluate the frequency of the loss of the Adenomatous Polyposis Coli (APC) protein and to compare the APC status with the characteristics of colorectal adenomas. METHODS: Immunohistochemical analysis of the APC protein was performed on 118 adenomas and the results were compared with parameters of malignant potential, location of adenomas, macroscopic appearance and age of the patients. RESULTS: A complete...

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Identifiers

PMID: 16804979
DOI: 10.3748/wjg.v12.i24.3901
PMCID: PMC4087942

Genes

APC

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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